http://www.nextprot.org/nanopubs#NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4
type: Nanopublication
created: 2014-09-19T00:00:00.0Z
rights: http://creativecommons.org/licenses/by/3.0/
rights holder: nextprot.org
used data: neXtProt database
authored by: CALIPHO project
authored by: http://orcid.org/0000-0001-6710-1373
authored by: 0000-0001-6818-334X
authored by: http://orcid.org/0000-0002-1303-2189
authored by: http://orcid.org/0000-0003-1813-6857
version number: 3

http://www.nextprot.org/nanopubs#NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4._1
type: SO_0001148
type: RangedSequencePosition
comment: Dominant-negative mutant. Induces increased number of binucleated cells, indicating defects in cytokinesis. Inhibits the transport of NPC1L1 to the plama membrane. Disrupts the trafficking of CDH1 to the plasma membrane and promotes accumulation of CDH1 in RAB11A endosomes in nonpolarized cells. Promotes mistargeting of CDH1 to the apical membrane in polarized cells.

http://www.nextprot.org/nanopubs#NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4._2
SIO_000300: 25
type: StartPosition

http://www.nextprot.org/nanopubs#NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4._3
SIO_000300: 25
type: EndPosition

http://www.nextprot.org/nanopubs#NX_P62491-1_MUTAGEN_25_25.RABRVrfPeidND-f8u8vTi6U5dmQvCh2XXkKOKDtQ0Tvo4.assertion
comment: Mutagenesis site occurs in NX_P62491-1 at amino acids 25 - 25.
used data: P62491
evidence: neXtProt gold
type: ECO_0000006
type: ECO_0000200

neXtProt gold
type: ECO_0000205