sub:assertion {
  sub:_1 sio:SIO_000053 sub:_2 , sub:_3 ;
    a so:SO_0001148 , range:RangedSequencePosition ;
    rdfs:comment "Dominant-negative mutant. Induces increased number of binucleated cells, indicating defects in cytokinesis. Inhibits the transport of NPC1L1 to the plama membrane. Disrupts the trafficking of CDH1 to the plasma membrane and promotes accumulation of CDH1 in RAB11A endosomes in nonpolarized cells. Promotes mistargeting of CDH1 to the apical membrane in polarized cells." .
  sub:_2 sio:SIO_000300 25 ;
    a range:StartPosition .
  sub:_3 sio:SIO_000300 25 ;
    a range:EndPosition .
  sub:assertion rdfs:comment "Mutagenesis site occurs in NX_P62491-1 at amino acids 25 - 25." .
  sub:seqFeature bfo:BFO_0000066 nx:NX_P62491-1 ;
    sio:SIO_000008 sub:_1 ;
    a so:SO_000010 .
}