. . . . . . . . . . . . "m(HGNC:MIR21) -> bp(GOBP:\"cell migration\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "miR-21 was noted to be highly overexpressed in HCC tumors and cell lines in expression profiling studies using a miRNA microarray. Inhibition of miR-21 in cultured HCC cells increased expression of the phosphatase and tensin homolog (PTEN) tumor suppressor, and decreased tumor cell proliferation, migration, and invasion. In contrast-enhanced miR-21 expression by transfection with precursor miR-21 increased tumor cell proliferation, migration, and invasion. PTEN was shown to be a direct target of miR-21, and to contribute to miR-21 effects on cell invasion. " . . "Selventa" . . . . "2014-07-03T14:33:12.183+02:00"^^ . . .