http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#Head http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#provenance http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#pubinfo http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6018 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_2 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_3 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11364 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D008264 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_2 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_1 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.w3.org/2000/01/rdf-schema#label p(HGNC:IL6) -> tscript(p(HGNC:STAT3)) http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_5 http://www.w3.org/ns/prov#value Stimulation of ABCA1-mediated cholesterol efflux by IL-6 was, however, abolished by selective inhibition of the Jak-2/Stat3 signaling pathway. In addition, we observed that the expression of molecules described to promote efferocytosis, i.e. c-mer proto-oncogene-tyrosine kinase, thrombospondin-1, and transglutaminase 2, was significantly induced in human macrophages upon treatment with IL-6. Consistent with these findings, IL-6 enhanced the capacity of human macrophages to phagocytose apoptotic cells; moreover, we observed that IL-6 stimulates the ABCA1-mediated efflux of cholesterol derived from the ingestion of free cholesterol-loaded apoptotic macrophages. http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/21757719 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/21757719 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#_5 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8#pubinfo http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://purl.org/dc/terms/created 2014-07-03T14:30:55.595+02:00 http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RABJ1dxVs_MafEMYtjGqehkzK6ZW1R51E7hwz-o0e0Ro8 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234