@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABDwAbRXAHkVbt6atLYCjiNNQ6pvtXxRguptTxczERtI> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABDwAbRXAHkVbt6atLYCjiNNQ6pvtXxRguptTxczERtI#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix rgd: <http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix schem: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasAgent: sub:_2;
    a go:0016301 .
  
  sub:_2 geneProductOf: rgd:3401;
    a Protein: .
  
  sub:_3 occursIn: obo:CL_0000187, obo:UBERON_0004237, species:10116;
    rdf:object schem:Calcium;
    rdf:predicate belv:decreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "kin(p(RGD:Prkg2)) -| a(SCHEM:Calcium)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_5;
    pav:version "20131211" .
  
  sub:_4 prov:value "cAMP and cGMP reduce [Ca2]i and relax smooth muscle through their cAMP- (PKA) and cGMP-activated (PKG) kinases (50, 410, 418). Several effects of cAMP are mediated by cross activation of PKG (50, 104), and significant components of the relaxant effects of cGMP are mediated through Ca2 desensitization (188) (Fig. 6). Inhibition of cAMP-induced Ca2 desensitization by a relatively selective PKG inhibitor also suggests that major effects of both cAMP and cGMP on the Ca2 sensitivity of myosin II are mediated by PKG, rather than PKA, whereas the nitric oxide (NO)-induced decrease in [Ca2]i is independent of PKG (418), and perhaps mediated by PKA cross-activated by cGMP.";
    prov:wasQuotedFrom pubmed:14506307 .
  
  sub:_5 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:14506307;
    prov:wasDerivedFrom beldoc:, sub:_4 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:32:09.402+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}