@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABBEe7NpbSYhkaMdcgh1k95m0eh_uniayawMWewqlRQo> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABBEe7NpbSYhkaMdcgh1k95m0eh_uniayawMWewqlRQo#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix schem: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix do: <http://disease-ontology.org/term/DOID:> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 geneProductOf: hgnc:3229 ;
    a Protein: .
  sub:_2 hasAgent: sub:_3 ;
    a go:0016301 .
  sub:_3 geneProductOf: hgnc:391 ;
    a Protein: .
  sub:_4 rdf:object sub:_2 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:_5 occursIn: do:1107 , obo:UBERON_0001043 , species:9606 ;
    rdf:object sub:_4 ;
    rdf:predicate belv:decreases ;
    rdf:subject schem:LY%20294002 ;
    a rdf:Statement .
  sub:assertion rdfs:label "a(SCHEM:\"LY 294002\") -| (p(HGNC:EGF) -> kin(p(HGNC:AKT1)))" , "p(HGNC:EGF) -> kin(p(HGNC:AKT1))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "20131211" .
  sub:_6 prov:value "We employed well established PI3K inhibitors, wortmannin and LY294002, to blunt the PI3K signaling pathway. The phosphorylation of Akt induced by EGF was totally abolished by preincubation with the PI3K inhibitors in TE-2, TE-8, and TE-10 cells (Fig. 6). " ;
    prov:wasQuotedFrom pubmed:10908564 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10908564 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:31:36.322+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}