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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#_3 http://www.w3.org/ns/prov#value We have previously demonstrated that thyroid hormone controls growth hormone synthesis in GH1 cells and that the induction of the growth hormone response by glucocorticoid appears to be highly dependent on thyroid hormone action.Thyroid hormone induces growth hormone synthesis approximately 5- to 20-fold and cortisol increases this response 2- to 6-fold further.Quantitation of growth hormone mRNA levels by cell-free protein synthesis demonstrates that the regulation of growth hormone synthesis by thyroid and glucocorticoid hormones is explained by a synergistic pretranslational control mechanism, presumably at the level of the growth hormone gene. http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/272661 http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/272661 http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#_3 http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok#pubinfo http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok http://purl.org/dc/terms/created 2014-07-03T14:33:43.070+02:00 http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAB8d4OPZu4LJtPUrBbYH2FyUqbARCSITTXTCieXig7Ok http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234