sub:assertion {
d:DB00541 dv:ddi-interactor-in dr:DB00541_DB01026 .
d:DB01026 dv:ddi-interactor-in dr:DB00541_DB01026 .
dr:DB00541_DB01026 dct:identifier "drugbank_resource:DB00541_DB01026" ;
dct:title "DDI between Vincristine and Ketoconazole - Ketoconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Ketoconazole is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Vincristine and Ketoconazole - Ketoconazole, a strong CYP3A4 inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Ketoconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00541_DB01026]"@en .
}