sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "20131211" .
  sub:_4 prov:value "Activation of NF-?B by H pylori induces nuclear translocation, which causes an increase in IL-8 messenger RNA and protein levels[50,53]. This has important implications since other NF-?B responsive genes including pro-inflammatory cytokines have been found in elevated levels in H pylori infected gastric mucosa. NF-?B activation is known to regulate cellular growth responses, including apoptosis, and is required for the induction of inflammatory and tissue-repair genes, including macrophage inflammatory protein (MIP)-2, metalloproteinase 3 (MMP3) and vascular endothelial growth factor (VEGF). The NF-?B pathway is also responsible for the generation of several cell adhesion molecules including ICAM-1 whose expression is signifi cantly correlated with an increase in H pylori induced gastritis[54]." ;
    prov:wasQuotedFrom pubmed:16718776 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16718776 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}