. . . . . . . . . . "bp(MESHPP:Apoptosis) -> path(SDIS:\"CD8+CD3+TCR+ naive T-cell differentiation\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Thymic tolerance depends on induction of apoptosis (programmed cell death) in immature thymocytes by antigen/MHC complexes on dendritic cells (and possibly other bone marrow-derived APCs). Interactions with antigen/MHC complexes on thymic epithelial cells promote maturation of double-positive thymocytes (CD4+CD8+CD3+TCR+) to single-positive cells (CD4+CD8-CD3+TCR+ and CD8+CD4-CD3+TCR+)." . . "Selventa" . . . . "2014-07-03T14:32:16.266+02:00"^^ . . .