@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAAZpW0paZaj0CjzZECrZ-V4bKKoaSUQPT06Rb2eV1qJw> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAAZpW0paZaj0CjzZECrZ-V4bKKoaSUQPT06Rb2eV1qJw#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix sdis: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-diseases/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 occursIn: obo:CL_0000809 , species:9606 ;
    rdf:object sdis:CD8%2BCD3%2BTCR%2B%20naive%20T-cell%20differentiation ;
    rdf:predicate belv:increases ;
    rdf:subject mesh:D017209 ;
    a rdf:Statement .
  sub:assertion rdfs:label "bp(MESHPP:Apoptosis) -> path(SDIS:\"CD8+CD3+TCR+ naive T-cell differentiation\")" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_3 ;
    pav:version "20131211" .
  sub:_2 prov:value "Thymic tolerance depends on induction of apoptosis (programmed cell death) in immature thymocytes by antigen/MHC complexes on dendritic cells (and possibly other bone marrow-derived APCs). Interactions with antigen/MHC complexes on thymic epithelial cells promote maturation of double-positive thymocytes (CD4+CD8+CD3+TCR+) to single-positive cells (CD4+CD8-CD3+TCR+ and CD8+CD4-CD3+TCR+)." ;
    prov:wasQuotedFrom pubmed:1482060 .
  sub:_3 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:1482060 ;
    prov:wasDerivedFrom beldoc: , sub:_2 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:32:16.266+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}