@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAAQo4NizaWOeLopiYTXexrl0LMKljyLt_WkFhSE1plIc> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAAQo4NizaWOeLopiYTXexrl0LMKljyLt_WkFhSE1plIc#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 geneProductOf: hgnc:6771 ;
    a Protein: .
  sub:_2 hasAgent: sub:_3 ;
    a go:0003824 .
  sub:_3 geneProductOf: hgnc:1504 ;
    a Protein: .
  sub:_4 occursIn: obo:CL_0000653 , species:9606 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:decreases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:SMAD5) -| cat(p(HGNC:CASP3))" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "20131211" .
  sub:_5 prov:value "TGF-beta raised caspase-3 activity which was blocked by BMP7 but enhanced by smad5 knockdown (Fig. 6B). Moreover, smad5 knockdown reduced the effects of BMP7. Overexpression of smad5 mimicked the effect of BMP7 on the prevention of TGF-beta-induced caspase-3 activation and further promoted the effects of BMP7 in experiments where exogenous BMP7 was added to smad5 overexpressing cells. Incubation of podocytes with high glucose (25 mM) for 24 h also enhances caspase-3 activity (Fig. 6C) which is thought to be mediated by TGF-beta" ;
    prov:wasQuotedFrom pubmed:17804487 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:17804487 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:33:12.382+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}