http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#Head http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#provenance http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#pubinfo http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.ncbi.nlm.nih.gov/gene/3630 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=8891 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0002107 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_2 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_1 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.w3.org/2000/01/rdf-schema#label p(EGID:3630) -> r(HGNC:PGD) http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_4 http://www.w3.org/ns/prov#value To address the effects of LXR signaling in human livers, we have used genome-wide expression profiling of primary human hepatocytes cultured at varying physiological concentrations of insulin and treated them with the synthetic LXR agonist GW3965. 85 genes were significantly upregulated and 105 genes were significantly downregulated by insulin and GW3965 treatment, respectively. 38 genes were significantly upregulated and 84 genes were significantly downregulated by insulin alone. Fold change was 1.5 increase or decrease compared to control. http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17628011 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17628011 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#_4 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y#pubinfo http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://purl.org/dc/terms/created 2014-07-03T14:33:11.789+02:00 http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAAISyyR33Gau9Y9mhT24GlpSmQ3N0sosTz_a0wxyld-Y http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234