@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAAIC9gQsRt45DP3e1lnu0jm_gubI5aUX36qBTVciyOqk> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAAIC9gQsRt45DP3e1lnu0jm_gubI5aUX36qBTVciyOqk#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: mgi:96180;
    a Protein: .
  
  sub:_2 geneProductOf: mgi:1858414;
    a RNA: .
  
  sub:_3 occursIn: atcc:CCL-92.aspx, species:10090;
    rdf:object sub:_2;
    rdf:predicate belv:decreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "p(MGI:Hoxa9) -| r(MGI:Ngef)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_5;
    pav:version "1.4" .
  
  sub:_4 prov:value "Blnk and Ifit1 showed no increase in either the HOXD13- or HOXA9-expressing cells. Given that Blnk had increased expression after transient HOXD13 expression, it is likely that the lack of a response may be due to low HOXD13 levels in this population of HOXD13 stable-expressing cells. Since the SQ RT-PCR assay is not as useful for detecting changes in expression of genes that are initially highly expressed in the EGFP-only cells, we did not test the expression of Fstl and Igfbp4. Ngef and Casp8ap2 had lower expression levels in the HOXA13/EGFP-expressing cells (Ngef, Fig. 2; Casp8ap2 decreased 1.3-fold, not shown). HOXD13- and HOXA9-expressing cells also had reduced expression of Ngef and Casp8ap2 (Fig. 7B) by a magnitude consistent with that observed by microarray for the HOXA13/EGFP-expressing cells (Table 3). Thus, these results demonstrate that group 13 HOX proteins were capable of upregulating a subset of the genes that HOXA9 could not, implying a paralog-specific regulatory effect. However, the repression of Ngef and Casp8ap2 was a shared property.  ";
    prov:wasQuotedFrom pubmed:15733672 .
  
  sub:_5 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:15733672;
    prov:wasDerivedFrom beldoc:, sub:_4 .
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sub:pubinfo {
  this: dct:created "2014-07-03T14:30:32.705+02:00"^^xsd:dateTime;
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}