http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#Head http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#provenance http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:108069 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D008168 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_1 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://bioportal.bioontology.org/ontologies/MSH/D004435 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.w3.org/2000/01/rdf-schema#label path(SDIS:"food intake") -| r(MGI:Ccna2) http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_3 http://www.w3.org/ns/prov#value Toward addressing this void, we used a mouse model in which calorie restriction produces alveolar loss, and ad libitum access to food after calorie restriction induces alveolar regeneration. We selected four processes (cell replication, angiogenesis, extracellular matrix remodeling, and guided cell motion) that would be required to convert a flat segment of alveolar wall into a septum that increases gas-exchange surface area. Global gene expression supportive of processes required to form a septum was present within 3 h of allowing calorie-restricted mice food ad libitum. One hour after providing calorie-restricted mice food ad libitum, RNA-level expression supportive of cell replication was present with little evidence of expression supportive of angiogenesis, extracellular matrix remodeling, or guided cell motion. Cell replication was more directly assayed by measuring DNA synthesis in lung. This measurement was made 3 h after allowing calorie-restricted mice food ad libitum because translation may be delayed. Ad libitum food intake, following calorie restriction, elevated DNA synthesis. (Table 2, 4, 6, 8, 10, 12, and 14) http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17237152 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17237152 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#_3 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://purl.org/dc/terms/created 2014-07-03T14:30:49.062+02:00 http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAAHTBVJw9bVA72lKVdYaH2wJjzl7Amu3NkfZWMU57Ofo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234