@prefix dct: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix hasPart: .
@prefix ProteinComplex: .
@prefix go: .
@prefix hasAgent: .
@prefix species: .
@prefix occursIn: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 hasPart: sub:_2, sub:_3;
a ProteinComplex: .
sub:_2 geneProductOf: hgnc:3113;
a Protein: .
sub:_3 geneProductOf: hgnc:9884;
a Protein: .
sub:_4 hasAgent: sub:_5;
a go:0042789 .
sub:_5 geneProductOf: hgnc:3113;
a Protein: .
sub:_6 occursIn: species:9606;
rdf:object sub:_4;
rdf:predicate belv:decreases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "complex(p(HGNC:E2F1),p(HGNC:RB1)) -| tscript(p(HGNC:E2F1))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_8;
pav:version "1.4" .
sub:_7 prov:value "(From full text) In another approach to indirectly activate endogenous E2F, we employed mutant SAOS2 cells expressing temperature-sensitive pRB [47]. Shift of the culture to permissive temperature, allows the formation of pRB-E2F1 complexes, which would prevent the function of E2F resulting in the derepression of the PAI-1 gene. Accordingly, we found that shift of the culture to the permissive temperature induced PAI-1 mRNA (Fig. 3)Go. In contrast, the temperature shift had no effect on PAI-1 gene expression in control SAOS-2 cells.";
prov:wasQuotedFrom pubmed:11559366 .
sub:_8 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:11559366;
prov:wasDerivedFrom beldoc:, sub:_7 .
}
sub:pubinfo {
this: dct:created "2014-07-03T14:29:58.176+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}