. . . . . . . . . . . . . . . . . . . . "complex(p(HGNC:E2F1),p(HGNC:RB1)) -| tscript(p(HGNC:E2F1))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "(From full text) In another approach to indirectly activate endogenous E2F, we employed mutant SAOS2 cells expressing temperature-sensitive pRB [47]. Shift of the culture to permissive temperature, allows the formation of pRB-E2F1 complexes, which would prevent the function of E2F resulting in the derepression of the PAI-1 gene. Accordingly, we found that shift of the culture to the permissive temperature induced PAI-1 mRNA (Fig. 3)Go. In contrast, the temperature shift had no effect on PAI-1 gene expression in control SAOS-2 cells." . . "Selventa" . . . . "2014-07-03T14:29:58.176+02:00"^^ . . .