. . . . . . . . . . . . "[PSEN1 gene mutations resulting in large increases in secreted Abeta42 levels or loss of PSEN1 exons 8 or 9 may cause Alzheimer disease with spastic paraparesis and cotton wool plaques.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2009-03-31"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2014-10-02T12:33:20+02:00"^^ . . . . . . . . . . . "v2.1.0.0" . "v2.1.0" .