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cat(p(HGNC:MMP2)) -> bp(GOBP:angiogenesis)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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MMP-2 binds to ?v?3 at the cell surface, and blocking this binding inhibits MMP-2 protease activity in cultured cells, suppressing angiogenesis and tumour growth in chorioallantoic membrane assays43.Conversely, the membrane MMP (MT-1) cleaves ?v?3, enhancing the ligand binding activity of this integrin44. So,?v?3 seems to be important in regulating angiogenesis in adult animals.
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Selventa
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2014-07-03T14:31:59.944+02:00
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