@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RA9gzq4RVpX2OaL_3ec3SY5Oe1jBX_msC1Z2IMnY5HvCs
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RA9gzq4RVpX2OaL_3ec3SY5Oe1jBX_msC1Z2IMnY5HvCs#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix schem: <
http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/
> .
@prefix obo: <
http://purl.obolibrary.org/obo/
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasPart: <
http://purl.obolibrary.org/obo/BFO_0000051
> .
@prefix ProteinComplex: <
http://amigo.geneontology.org/amigo/term/GO:0043234
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasPart:
sub:_2
,
sub:_3
;
a
ProteinComplex:
.
sub:_2
geneProductOf:
hgnc:11439
;
a
Protein:
.
sub:_3
geneProductOf:
hgnc:19694
;
a
Protein:
.
sub:_4
occursIn:
mesh:D002462
,
obo:UBERON_0002385
,
species:9606
;
rdf:object
sub:_1
;
rdf:predicate
belv:decreases
;
rdf:subject
schem:serum%20insulin
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"a(SCHEM:\"serum insulin\") -| complex(p(HGNC:STX4),p(HGNC:STXBP4))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"20131211" .
sub:_5
prov:value
"Several proteins have been shown to bind to Syn4, including SNAP23, Munc18c, and Synip, and thereby to regulate the docking and fusion of VAMP2-containing Glut4 vesicles. Among these, Synip has been shown to interact with Syn4 under basal conditions and then to dissociate from it in response to insulin. Because Synip competes for VAMP2 binding, the dissociation of Synip is thought to allow VAMP2 to bind to Syn4 and might provide a signal for the docking of the Glut4 vesicle." ;
prov:wasQuotedFrom
pubmed:11849969
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:11849969
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dcterms:created
"2014-07-03T14:31:47.024+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}