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complex(p(HGNC:CAMLG),p(HGNC:PPIB)) -| phos(complex(SCOMP:"Calcineurin Complex"))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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CAMLG harvester omim
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CAMLG harvester omim
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Online Resource
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Pubmed titles from omim summary: (summary is not available from this source) Entrez Gene GeneRifs summary: Human: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium.
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2014-07-03T14:31:27.938+02:00
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