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[Osteogenesis imperfecta (OI) is a heritable bone fragility disorder that in the majority of cases is caused by mutations in COL1A1 or COL1A2, the genes that encode the two collagen type I alpha chains, alpha1(I) and alpha2(I).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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