. . . . . . . . . . . "p(HGNC:PARP1) -| bp(MESHPP:Apoptosis)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Collectively, these studies suggest that the persistent single-strand breaks formed upon PARP-1 inhibition, which promote the collapse of replication forks and would normally be repaired by homologous recombination, cannot be repaired effectively in the absence of functional BRCA1 or BRCA2. This results in the accumulation of chromosomal abnormalities, cell cycle arrest in G2/M, and apoptosis" . . "Selventa" . . . . "2014-07-03T14:30:37.920+02:00"^^ . . .