@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RA7rt8iKaoyDNERiwgLWGGIJWW3o3flb-nZyVHtuEU5N0
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RA7rt8iKaoyDNERiwgLWGGIJWW3o3flb-nZyVHtuEU5N0#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
geneProductOf:
hgnc:270
;
a
Protein:
.
sub:_2
occursIn:
species:9606
;
rdf:object
mesh:D017209
;
rdf:predicate
belv:decreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"p(HGNC:PARP1) -| bp(MESHPP:Apoptosis)" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_4
;
pav:version
"1.4" .
sub:_3
prov:value
"Collectively, these studies suggest that the persistent single-strand breaks formed upon PARP-1 inhibition, which promote the collapse of replication forks and would normally be repaired by homologous recombination, cannot be repaired effectively in the absence of functional BRCA1 or BRCA2. This results in the accumulation of chromosomal abnormalities, cell cycle arrest in G2/M, and apoptosis" ;
prov:wasQuotedFrom
pubmed:16140981
.
sub:_4
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:16140981
;
prov:wasDerivedFrom
beldoc:
,
sub:_3
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:37.920+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}