http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_head http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_provenance http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://identifiers.org/ncbigene/1636 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0151744 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN35a805db3fe7e7d03eb323b3118735e7 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/1636 http://rdf.disgenet.org/resource/gda/DGN35a805db3fe7e7d03eb323b3118735e7 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0151744 http://rdf.disgenet.org/resource/gda/DGN35a805db3fe7e7d03eb323b3118735e7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_provenance http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://purl.org/dc/terms/description [In the last two decades ACE gene has been cloned that allowed the identification (i) of two isoenzymes, one called somatic ACE resulting from gene duplication and primarily expressed in endothelial cells, and the other, called germinative or testicular ACE, resulting from the transcription in the male reproductive system of a more simple gene, (ii) of an hydrophobic C-terminal peptide for membrane-anchoring and specifically cleaved by a metalloprotease to release soluble forms of both isoenzymes, and (iii) of several allelic polymorphisms, one of them consisting of an insertion/deletion (I/D) polymorphism in a short intronic Alu sequence that could account for half the variance in plasma ACE level and resulting in a large inter-individual variability; moreover this I/D polymorphism was proposed as a genetic marker for identifying individuals at high risk of ischemic heart disease and of anticipating in one individual the efficacy of the antihypertensive therapy, although conflicting data arose from the past decade literature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/12005216 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v4.0.0/void/befree-2016 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v4.0.0/void/befree-2016 http://purl.org/pav/importedOn 2016-02-19 http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v4.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/dc/terms/created 2016-05-13T12:44:26+02:00 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v4.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v4.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP354429.RA7RlbbYsNSR4Be81W69eiFUYCsZyH6OeBLt6YpkuFhfs http://purl.org/pav/version v4.0.0.0 http://rdf.disgenet.org/v4.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v4.0.0