@prefix this: . @prefix sub: . @prefix prov: . @prefix dct: . @prefix pav: . @prefix orcid: . @prefix codebase: . @prefix version: . @prefix instance: . @prefix process: . @prefix np: . @prefix rdfs: . @prefix xsd: . @prefix v: . @prefix d: . @prefix dv: . @prefix dr: . @prefix dcat: . @prefix npx: . sub:head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:publicationInfo; a np:Nanopublication . } sub:assertion { d:DB05200 v:identifier "DB05200"; v:namespace "drugbank"; v:uri "http://bio2rdf.org/drugbank:DB05200"; v:x-identifiers.org ; dv:drugbank-id "DB05200"; dv:x-cas ; dct:description "AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones. It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA). GAA to the lysosome, where it can perform its normal function. AT2220 has been shown to increase GAA activity in cell lines derived from Pompe patients and in transfected cells expressing misfolded forms of GAA."@en; dct:identifier "drugbank:DB05200"; dct:title "AT2220"@en; a dv:Drug; rdfs:label "AT2220 [drugbank:DB05200]"@en; rdfs:seeAlso . } sub:provenance { sub:assertion prov:wasDerivedFrom . dr:bio2rdf.dataset.drugbank.R3 dcat:distribution . dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime; prov:wasDerivedFrom . pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime; prov:wasDerivedFrom . prov:wasAttributedTo . } sub:publicationInfo { sub:signature.MCwCFFZSZxLWQti5 npx:hasPublicKey "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"; npx:hasSignature "MCwCFFZSZxLWQti5RE/5k7tfGTX6c+6RAhRtuatnaIb6UMCNsToNc0BpWXpLPw=="; npx:signedBy instance: . this: dct:created "2018-03-30T11:11:08.627+02:00"^^xsd:dateTime; dct:license ; npx:hasSignatureElement sub:signature.MCwCFFZSZxLWQti5; prov:wasGeneratedBy process: . instance: prov:specializationOf codebase:; prov:wasAttributedTo orcid:0000-0002-1267-0234 . process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475"; prov:used version:; prov:wasAssociatedWith instance:; prov:wasStartedBy orcid:0000-0002-1267-0234 . version: dct:isVersionOf codebase:; pav:version "eda7951a5f6c622c5d2132f50c3093138484a349"; prov:wasAttributedTo orcid:0000-0002-1267-0234 . }