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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#_5 http://www.w3.org/ns/prov#value Stimulation of platelets with the PAR-1 agonist SFLLRN resulted in rapid and transient phosphorylation of PDE3A on Ser(312), Ser(428), Ser(438), Ser(465), and Ser(492). Furthermore, phosphorylation and activation of PDE3A required the activation of PKC, but not of PI3K/PKB, mTOR/p70S6K, or ERK/RSK. Activation of PKC by phorbol esters also resulted in phosphorylation of the same PDE3A sites in a PKC-dependent manner. http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/19261611 http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/19261611 http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#_5 http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98#pubinfo http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98 http://purl.org/dc/terms/created 2014-07-03T14:33:33.470+02:00 http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA7IreMkvy_MLfu0D1B7Ytpq3-4MDndtZdrKCkLLr1x98 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234