[cleavage of p35 to p25 greatly enhances the kinase activity of CDK5 and increases the phosphorylation of Ser (202)/Thr (205) and may play a pivotal role in neuronal cell death in Alzheimer's disease ]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
Gene-disease associations inferred from text-mining the literature.
DisGeNET evidence - LITERATURE