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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#_4 http://www.w3.org/ns/prov#value Using histidine decarboxylase gene targeted (HDC(-/-)) BALB/c mice, we studied the effect of the absence of histamine on four cytochrome p450 enzyme activities. Their selective substrates were measured: ethoxyresorufin O-dealkylase activity of CYP1A, pentoxyresorufin O-dealkylase activity of CYP2B, chlorzoxazone 6-hydroxylase activity of CYP2E1 and ethylmorphine N-demethylase activity of CYP3A.The results indicate a significant elevation of CYP2E1 and CYP3A activities http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/14642533 http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/14642533 http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#_4 http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc#pubinfo http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc http://purl.org/dc/terms/created 2014-07-03T14:30:18.613+02:00 http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA6uWwr4yKxSpOmJxOZzFR5CEPnGxXj9ogsJQcrc4-duc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234