sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "1.4" .
  sub:_6 prov:value "histone-modifying proteins, such as arginine methyltransferases, also act as co-activators for nuclear receptors, including ER, either through direct interaction with the LBD56 or through association with co-activators 57,58. Anti-oestrogens fall into two broad categories. The first class, exemplified by tamoxifen and raloxifene, inhibits AF2 activation and thereby ER activity, but does not prevent activation of AF1. Because the ER activity in breast epithelium is due mainly to AF2, tamoxifen acts largely as an antagonist in breast cells, whereas in other tissues, such as the uterus, AF1 activity is more significant, resulting in greater agonistic activity." ;
    prov:wasQuotedFrom pubmed:12635173 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12635173 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}