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[High concentrations of type I IFNs may block B cell responses or lead to the production of immunosuppressive molecules, and such concentrations also reduce the responsiveness of macrophages to activation by IFN?, as has been shown for infections with Listeria monocytogenes and Mycobacterium tuberculosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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