. . . . . . . . . . . . . . "path(SDIS:\"bacterial infection\") -> cat(p(HGNC:TLR4))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "from full text - We previously showed that TL1A is induced by the Fc?R signaling pathway [45]. Recently, the potential interaction of TL1A in microbial-host interaction was illustrated by a report showing microbial organisms can induce TL1A in APCs [46]. Microbial-activated TL1A was in part mediated by TLR 1, 2, 4, and 9 signaling pathways and dependent on downstream p38 MAP kinase and NF-kappaB activation (Fig. 1) [46]. Negative regulators of the TL1A signaling pathway also exist and may serve to maintain gut immune homeostasis. Our group showed that TLR8 or TLR7/8 ligand (R848) can inhibit TL1A production in a dose dependent manner [47•]." . . "Selventa" . . . . "2014-07-03T14:33:37.516+02:00"^^ . . .