@prefix this: <http://www.tkuhn.ch/bel2nanopub/RA5Q02RekNWUbtnQ_Ur2uWmiEVWvLBQNmJRMLgBv0Kn3Y> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RA5Q02RekNWUbtnQ_Ur2uWmiEVWvLBQNmJRMLgBv0Kn3Y#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasAgent: sub:_2;
    a go:0003824 .
  
  sub:_2 geneProductOf: hgnc:285;
    a Protein: .
  
  sub:_3 hasAgent: sub:_4;
    a go:0005525 .
  
  sub:_4 geneProductOf: hgnc:4392;
    a Protein: .
  
  sub:_5 occursIn: obo:CL_0000746, obo:UBERON_0000948, species:9606;
    rdf:object sub:_3;
    rdf:predicate belv:directlyIncreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "cat(p(HGNC:ADRB1)) => gtp(p(HGNC:GNAS))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_8;
    pav:version "20131211" .
  
  sub:_6 dce:identifier "Golan Document";
    dce:title "Golan Document";
    dce:type "Other" .
  
  sub:_7 prov:value "Binding of an endogenous or exogenous agonist to beta 1-adrenergic receptors on the surface of cardiac myocytes causes G alpha proteins to activate adenylyl cyclase, which in turn catalyzes the conversion of ATP to cAMP. cAMP activates multiple protein kinases, including protein kinase A. PKA phosphorylates and activates sarcolemmal Ca2+ channels and thereby increases cardiac myocyte contractility.";
    prov:wasQuotedFrom sub:_6 .
  
  sub:_8 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource sub:_6;
    prov:wasDerivedFrom beldoc:, sub:_7 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:31:29.112+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}