. . . . . . . "[Here, the in vivo effects of Klf4 deletion were examined from the mouse intestinal epithelium (Klf4(?IS)) in a genetic or pharmacological setting of colonic tumorigenesis:Apc(Min/?) mutation or carcinogen treatment with azoxymethane (AOM), respectively.Klf4 (?IS)/Apc (Min/?) mice developed significantly more colonic adenomas with 100% penetrance as compared with Apc(Min/?) mice with intact Klf4 (Klf4(fl/fl)/Apc (Min/?)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:17:42+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .