@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_head {
  this: np:hasAssertion dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_assertion;
    np:hasProvenance dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_provenance;
    np:hasPublicationInfo dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_assertion a np:Assertion .
  
  dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_provenance a np:Provenance .
  
  dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_assertion {
  miriam-gene:673 a ncit:C16612 .
  
  lld:C0007115 a ncit:C7057 .
  
  dgn-gda:DGN972bc5b4c0dd32294734e70f4c78da1d sio:SIO_000628 miriam-gene:673, lld:C0007115;
    a sio:SIO_001122 .
}

dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_provenance {
  dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_assertion dcterms:description
      "[Our findings not only reveal an epigenetic mechanism for BRAF V600E-promoted NIS silencing involving histone deacetylation at critical regulatory regions of the NIS promoter but also provide further support for our previously proposed combination therapy targeting major signaling pathways and histone deacetylase to restore thyroid gene expression for radioiodine treatment of thyroid cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:24243688;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1128883.RA5GgvnsXisMhLu6zBuZLNH3_oGmftxr6S5J-SEYTFCB0130_publicationInfo {
  this: dcterms:created "2016-05-13T12:50:18+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}