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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#_2 http://www.w3.org/ns/prov#value The lpr gene has been identified as a defect in the Fas gene, which encodes a lymphocyte surface protein associated with apoptosis and shares homology with the tumor necrosis factor-alpha receptor. This finding is important as it may quickly lead to identification of the gld gene product, which is thought to be a ligand for Fas. Also, it clearly identifies autoimmune disease as originating from a defect in the ability to induce cell death in lymphocytes. http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/1419495 http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/1419495 http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#_2 http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw#pubinfo http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw http://purl.org/dc/terms/created 2014-07-03T14:32:09.133+02:00 http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA5EWDO7ptBz78xa5_hgX7BSRfsuEx3LczdS75rSxiZLw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234