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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#_3 http://www.w3.org/ns/prov#value Incubation...with LA, PA, and SA significantly increased Mo LPL mRNA expression. expose of macrophages to AA and EPA dramatically decreased LPL mRNA levels... These results suggest that FAs, including PA, SA, and AA, might exert their regulatory effect on Mo LPL gene expression, at least partly, through a PPAR-dependent mechanism. Indeed, we found that these well-characterized ligands and activators of PPARs (49) directly regulate Mo LPL gene expression and enhance the binding activity of nuclear proteins to the PPRE element present in the LPL gene in a PPAR-specific manner. http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11246888 http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11246888 http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#_3 http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4#pubinfo http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4 http://purl.org/dc/terms/created 2014-07-03T14:31:40.172+02:00 http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA5EVCk9NJKw6zHPkH1Vn7Q4uSz1MC_2ejBX1UkI8uls4 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234