sub:assertion { d:DB00458dv:ddi-interactor-indr:DB00458_DB00503 . d:DB00503dv:ddi-interactor-indr:DB00458_DB00503 . dr:DB00458_DB00503dct:identifier "drugbank_resource:DB00458_DB00503" ; dct:title "DDI between Imipramine and Ritonavir - Ritonavir may increase the effect and toxicity of the tricyclic antidepressant, imipramine, by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of imipramine if ritonavir if initiated, discontinued or dose changed."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Imipramine and Ritonavir - Ritonavir may increase the effect and toxicity of the tricyclic antidepressant, imipramine, by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of imipramine if ritonavir if initiated, discontinued or dose changed. [drugbank_resource:DB00458_DB00503]"@en . }