@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix chebi: . @prefix obo: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 occursIn: obo:UBERON_0004801, species:9606; rdf:object chebi:26523; rdf:predicate belv:increases; rdf:subject chebi:5586; a rdf:Statement . sub:assertion rdfs:label "a(CHEBI:\"hydrogen peroxide\") -> a(CHEBI:\"reactive oxygen species\")" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_3; pav:version "20131211" . sub:_2 prov:value "It is well known that addition of H2O2 can cause oxidative stress and cell death since it easily permeates through the membranes. For the same reason, H2O2 added to a cell culture is quickly decomposed due to activity of catalase and other cellular H2O2-consuming systems. For example, we found that 20 ?M H2O2 added to a culture of HeLa cells was completely decomposed in 15?20 min [19]. On the other hand, significant accumulation of ROS in the H2O2-treated cells was detected 45 min after addition of peroxide (Fig. 7), indicating activation of endogenous ROS production by added H2O2. "; prov:wasQuotedFrom pubmed:16678116 . sub:_3 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:16678116; prov:wasDerivedFrom beldoc:, sub:_2 . } sub:pubinfo { this: dct:created "2014-07-03T14:33:00.269+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }