sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_3 ;
    pav:version "20131211" .
  sub:_2 prov:value "It is well known that addition of H2O2 can cause oxidative stress and cell death since it easily permeates through the membranes. For the same reason, H2O2 added to a cell culture is quickly decomposed due to activity of catalase and other cellular H2O2-consuming systems. For example, we found that 20 ?M H2O2 added to a culture of HeLa cells was completely decomposed in 15?20 min [19]. On the other hand, significant accumulation of ROS in the H2O2-treated cells was detected 45 min after addition of peroxide (Fig. 7), indicating activation of endogenous ROS production by added H2O2. " ;
    prov:wasQuotedFrom pubmed:16678116 .
  sub:_3 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16678116 ;
    prov:wasDerivedFrom beldoc: , sub:_2 .
}