@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_head { this: np:hasAssertion dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_assertion; np:hasProvenance dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_provenance; np:hasPublicationInfo dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_publicationInfo; a np:Nanopublication . dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_assertion a np:Assertion . dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_provenance a np:Provenance . dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_publicationInfo a np:PublicationInfo . } dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_assertion { miriam-gene:4286 a ncit:C16612 . lld:C0025202 a ncit:C7057 . dgn-gda:DGNb713dac9a7269ed6d4a04401e6dc8838 sio:SIO_000628 miriam-gene:4286, lld:C0025202; a sio:SIO_001121 . } dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_provenance { dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_assertion dcterms:description "[It is widely held that cells with metastatic properties such as invasiveness and expression of matrix metalloproteinases arise through the stepwise accumulation of genetic lesions arising from genetic instability and clonal evolution. By contrast, we show here that in melanomas invasiveness can be regulated epigenetically by the microphthalmia-associated transcription factor, Mitf, via regulation of the DIAPH1 gene encoding the diaphanous-related formin Dia1 that promotes actin polymerization and coordinates the actin cytoskeleton and microtubule networks at the cell periphery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:17182868; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP585445.RA4rjD2fDDmdZuXxy4kcRM_3HHh87FxDpxtP2lC5-scbw130_publicationInfo { this: dcterms:created "2016-05-13T12:46:10+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }