@prefix this: <
http://bio2rdf.org/drugbank:DB04858_nanopub.RA4ozFmyZBSfDfJ9PsECD7d16LMJdCbqsXa90nM2qZtH0
> .
@prefix sub: <
http://bio2rdf.org/drugbank:DB04858_nanopub.RA4ozFmyZBSfDfJ9PsECD7d16LMJdCbqsXa90nM2qZtH0#
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix orcid: <
http://orcid.org/
> .
@prefix codebase: <
https://github.com/tkuhn/bio2rdf2nanopub
> .
@prefix version: <
https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349
> .
@prefix instance: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB
> .
@prefix process: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix v: <
http://bio2rdf.org/bio2rdf_vocabulary:
> .
@prefix d: <
http://bio2rdf.org/drugbank:
> .
@prefix dv: <
http://bio2rdf.org/drugbank_vocabulary:
> .
@prefix dr: <
http://bio2rdf.org/drugbank_resource:
> .
@prefix dcat: <
http://www.w3.org/ns/dcat#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:publicationInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
d:DB04858
v:identifier
"DB04858" ;
v:namespace
"drugbank" ;
v:uri
"http://bio2rdf.org/drugbank:DB04858" ;
v:x-identifiers.org
<
http://identifiers.org/drugbank/DB04858
> ;
dv:drugbank-id
"DB04858" ;
dv:x-cas
<
http://bio2rdf.org/cas:27314-97-2
> ;
dv:x-chemspider
<
http://bio2rdf.org/chemspider:31132
> ;
dv:x-pubchemcompound
<
http://bio2rdf.org/pubchem.compound:33776
> ;
dv:x-pubchemsubstance
<
http://bio2rdf.org/pubchem.substance:10426937
> ;
dv:x-wikipedia
<
http://bio2rdf.org/wikipedia:Tirapazamine
> ;
dct:description
"Tirapazamine (SR-4233) is an experimental anticancer drug that is activated to a toxic radical only at very low levels of oxygen (hypoxia). Such levels are common in human solid tumors, a phenomenon known as tumor hypoxia. Thus, tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective. As of 2006, tirapazamine is undergoing phase III testing in patients with head and neck cancer and gynecological cancer, and similar trials are being undertaken for other solid tumor types. [Wikipedia]"@en ;
dct:identifier
"drugbank:DB04858" ;
dct:title
"Tirapazamine"@en ;
a
dv:Drug
;
rdfs:label
"Tirapazamine [drugbank:DB04858]"@en ;
rdfs:seeAlso
<
http://www.drugbank.ca/drugs/DB04858
> .
}
sub:provenance
{
sub:assertion
prov:wasDerivedFrom
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
dr:bio2rdf.dataset.drugbank.R3
dcat:distribution
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
>
dct:created
"2015-01-09T17:00:50-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
>
pav:retrievedOn
"2014-11-12T07:57:03-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
>
prov:wasAttributedTo
<
http://drugbank.ca
> .
}
sub:publicationInfo
{
sub:signature.MC0CFQCOcVaRCNon
npx:hasPublicKey
"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" ;
npx:hasSignature
"MC0CFQCOcVaRCNonzdULzHwe8LDSwAjp/QIUeHTVk2/aJh1zl7E83hvkIoaD954=" ;
npx:signedBy
instance:
.
this:
dct:created
"2018-03-30T11:10:44.031+02:00"^^
xsd:dateTime
;
dct:license
<
https://creativecommons.org/licenses/by-nc/4.0/
> ;
npx:hasSignatureElement
sub:signature.MC0CFQCOcVaRCNon
;
prov:wasGeneratedBy
process:
.
instance:
prov:specializationOf
codebase:
;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
process:
dct:identifier
"7720f136-841b-4851-a6e4-ad20a409a475" ;
prov:used
version:
;
prov:wasAssociatedWith
instance:
;
prov:wasStartedBy
orcid:0000-0002-1267-0234
.
version:
dct:isVersionOf
codebase:
;
pav:version
"eda7951a5f6c622c5d2132f50c3093138484a349" ;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
}