sub:assertion { d:DB00641dv:ddi-interactor-indr:DB00641_DB08827 . d:DB08827dv:ddi-interactor-indr:DB00641_DB08827 . dr:DB00641_DB08827dct:identifier "drugbank_resource:DB00641_DB08827" ; dct:title "DDI between Simvastatin and Lomitapide - Simvastatin plasma concentrations are doubled by lomitapide. To prevent dose related adverse effects such as myopathy and rhabdomyolysis it is recommended to reduce the dose of simvastatin by 50%. See FDA label for additional dosage instructions."@en ; adv:Drug-Drug-Interaction ; rdfs:label """DDI between Simvastatin and Lomitapide - Simvastatin plasma concentrations are doubled by lomitapide. To prevent dose related adverse effects such as myopathy and rhabdomyolysis it is recommended to reduce the dose of simvastatin by 50%. See FDA label for additional dosage instructions. [drugbank_resource:DB00641_DB08827]"""@en . }