@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_head {
  this: np:hasAssertion dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_assertion;
    np:hasProvenance dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_provenance;
    np:hasPublicationInfo dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_assertion a np:Assertion .
  
  dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_provenance a np:Provenance .
  
  dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_assertion {
  miriam-gene:4842 a ncit:C16612 .
  
  lld:C0151814 a ncit:C7057 .
  
  dgn-gda:DGN5218c5f404cd7cd7de0fc225830a74c6 sio:SIO_000628 miriam-gene:4842, lld:C0151814;
    a sio:SIO_001121 .
}

dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_provenance {
  dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_assertion dcterms:description
      "[We observed that (1) pretreatment of rabbits 24 hours earlier with CCPA (100 microgram/kg IV bolus) or IB-MECA (100 or 300 microgram/kg) resulted in an approximately 35% to 40% reduction in the size of the infarct induced by 30 minutes of coronary artery occlusion and 72 hours of reperfusion compared with vehicle-treated rabbits, whereas pretreatment with the selective A(2A)AR agonist CGS 21680 (100 microgram/kg) had no effect; (2) the delayed cardioprotective effect of CCPA, but not that of IB-MECA, was completely blocked by coadministration of the highly selective A(1)AR antagonist N-0861; (3) inhibition of nitric oxide synthase (NOS) with N(omega)-nitro-L-arginine during the 30-minute occlusion abrogated the infarct-sparing action of CCPA but not that of IB-MECA; and (4) inhibition of ATP-sensitive potassium (K(ATP)) channels with sodium 5-hydroxydecanoate during the 30-minute occlusion blocked the cardioprotective effects of both CCPA and IB-MECA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:11249876;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP484365.RA4_VSli3kAx1b1cPALmw84JL1OiJHzfJThMyeYiS6Q8g130_publicationInfo {
  this: dcterms:created "2014-10-02T12:36:49+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}