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[Focal hypermethylation occurs at CpG islands in the promoters of certain genes including GSTP1, RAR?2, and RASSF1A with both age and cancer, while global hypomethylation is seen in prostate cancer and known to occur in the colon and other organs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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