http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#Head http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#provenance http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#pubinfo http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/TORC1%20Complex http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_2 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_2 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/AKT%20Family http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_3 http://semanticscience.org/resource/SIO_000139 http://resource.belframework.org/belframework/20131211/namespace/selventa-named-complexes/TORC1%20Complex http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_3 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_1 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://www.w3.org/2000/01/rdf-schema#label kin(p(SFAM:"AKT Family")) -> kin(complex(SCOMP:"TORC1 Complex")) http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_5 http://www.w3.org/ns/prov#value The connection between TOR and PI3K is revealed by the observation that Akt, which is activated by the PI3K pathway, phosphorylates and inhibits TSC2 (19?21). Furthermore, the understanding of the molecular function of TSC1/2 in regulating TORC1 was significantly advanced when Ras homology enriched in brain (Rheb) was identified as a key component acting downstream of TSC1/2 and upstream of TOR (22?27)... Therefore, a signaling pathway of PI3K-Akt-TSC2-Rheb-TORC1 has been proposed. (from full text) http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/16627617 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/16627617 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#_5 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q#pubinfo http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://purl.org/dc/terms/created 2014-07-03T14:32:59.879+02:00 http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RA4Mr6caimG2TkYDq5UX7GOAtVuQCZhb3-mfw9ZfBBJ1Q http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234