sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "20131211" .
  sub:_3 prov:value "five proteins previously identified to be downstream of Akt at the time of maximal nicotinic Akt induction: a member of the forkhead transcription factor family (FKHR), GSK-3? and -3?, a ribosomal kinase (p70S6K), and a binding protein for eukaryotic translation initiation factor 4E (4EBP-1) (Figure 2b). We observed different patterns of phosphorylation induced by nicotine or NNK. Nicotine increased the phosphorylation of all downstream substrates, but phosphorylation of GSK-3? and FKHR was induced most. NNK increased phosphorylation of all downstream substrates except FKHR and had the greatest effects on phosphorylation of GSK-3? and p70S6K" ;
    prov:wasQuotedFrom pubmed:12511591 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12511591 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}