@prefix this: <http://www.tkuhn.ch/bel2nanopub/RA3o_MzKdPWKTSellzJwuBamL-BdcByytgf0kyakYOA24> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RA3o_MzKdPWKTSellzJwuBamL-BdcByytgf0kyakYOA24#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix chebi: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasAgent: sub:_2;
    a go:0003824 .
  
  sub:_2 geneProductOf: hgnc:7891;
    a Protein: .
  
  sub:_3 geneProductOf: hgnc:11892;
    a Protein: .
  
  sub:_4 rdf:object chebi:26523;
    rdf:predicate belv:increases;
    rdf:subject sub:_3;
    a rdf:Statement .
  
  sub:_5 occursIn: obo:CL_0000057, obo:UBERON_0002048, species:9606;
    rdf:object sub:_4;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "cat(p(HGNC:NOX4)) -> (p(HGNC:TNF) -> a(CHEBI:\"reactive oxygen species\"))",
      "p(HGNC:TNF) -> a(CHEBI:\"reactive oxygen species\")" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_7;
    pav:version "20131211" .
  
  sub:_6 prov:value "Studies in pulmonary fibroblasts and smooth muscle cells revealed the expression of p47phox, p67phox, p22phox and NOX4, and demonstrated increased production of ROS in response to inflammatory mediators, such as tumor necrosis factor ? (TNF-?) or transforming growth factor ? (TGF-?), which is primary associated with selective upregulation of NOX4 (185–188).";
    prov:wasQuotedFrom pubmed:18164271 .
  
  sub:_7 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:18164271;
    prov:wasDerivedFrom beldoc:, sub:_6 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:33:14.300+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}