@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_head {
  this: np:hasAssertion dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_assertion;
    np:hasProvenance dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_provenance;
    np:hasPublicationInfo dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_assertion a np:Assertion .
  
  dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_provenance a np:Provenance .
  
  dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_assertion {
  miriam-gene:6347 a ncit:C16612 .
  
  lld:C0035304 a ncit:C7057 .
  
  dgn-gda:DGNbf0b5a118272c9fd641eba69244c2777 sio:SIO_000628 miriam-gene:6347, lld:C0035304;
    a sio:SIO_001121 .
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dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_provenance {
  dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_assertion dcterms:description
      "[Systemic monocytes, tissue resident macrophages, dendritic cells and microglia have specific roles in immune surveillance and maintenance of tissue homeostasis and are key regulator and effector cells of the local immune response to acute and chronic tissue injury.Two major signalling pathways that differentially define trafficking behaviour and activation of systemic and local myeloid cell populations in response to exogenous and endogenous inflammatory stimuli are the Ccl2-Ccr2 and the Cx3cl1-Cx3cr1 chemokine pathways.Alterations in these pathways have been implicated in controlling myeloid cell activation during normal ageing and in age-related retinal degenerations, including age-related macular degeneration (AMD).We review the evidence for how altered chemokine signalling in acute and chronic inflammatory conditions regulate local and systemic myeloid cell responses in the retina and how this may contribute to or attenuate pathology in inherited and age-related retinal diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:24664727;
    prov:wasDerivedFrom dgn-void:befree-20150227;
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  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP684561.RA3BoE8k1RYD_aSDzsuUD-fRiXQ1xPfhEXof5tRbt4TRE130_publicationInfo {
  this: dcterms:created "2015-08-25T14:44:32+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
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  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}