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[In the latter case, h-R3 treatment (0.25-1 mg/mouse; every other day per 2 weeks) not only significantly reduced VEGF mRNA expression of A431 tumors growing subcutaneously in SCID mice but also resulted in reduction of the overall microvascular density (MVD), disappearance of dilated 'mother vessels,' as well as in suppression of tumor growth followed by regression of established tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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